She reveals why it was joyful, yet tricky to film

It's a weird opportunity to play someone else ... playing someone else!

Mayim shot a video from the set after learning of the show's final season

Season 12 will be the show's last—and she has strong emotions about it

A Grok Nation reader shares his experience living with a disease

Mayim interviews her "Big Bang Theory" co-star about his new film with Meryl Streep

Go behind the scenes with Mayim